![]() Parents report safety as the primary reason for supplying their children with cell phones, whereas children place a greater value on the technological capabilities of the cell phone and its potential to facilitate socialization ( ![]() In contrast, regarding school emergencies or schedule changes, parents have often demanded immediate communication, which cell phones can provide ( Parents characteristically agree with school policy and want their children to abide by the rules ( The challenge faced by many administrators is to effectively balance the needs of the school with the demands of the students and the parents. For these reasons, students are not allowed to visibly possess cell phones within most high school classrooms. The existing possibility of posting improper photos on the Internet is also a cause for concern ( Cell phones ringing during a class time present unwanted distractions and, for some students, sending or receiving text messages can lead to cheating ( Administrators often are concerned about inappropriate use of cell phones in schools and this is the major cause of restricting their use ( Knowledge of students’ attitudes could possibly lead to, aid in, and influence future decision making regarding the implementation of cell phone use for academic purposes within high school classrooms.Īdministrators and teachers often regard the use of cell phones by students at school as a deterrent to student learning ( Students’ personal and social cell phone use has been well established, but how do high school students reflect on the usage of such phones in an educational setting? Determining student perception toward using the educational technological capabilities of cell phones within a learning environment is a first step. As a result of the rapidly occurring technological advances within the cell phone industry, schools have been hard pressed to make and keep current educational policy regarding the use of cell phones ( Other schools report changing policy from banning cell phone use to allowing students to use them before or after school ( ![]() School policy regarding cell phones, within the majority of public schools in the United States, is generally quite prohibitive and requires students to leave their cell phones at home or turn them off and leave them in their lockers during the school day ( Perceptional gender differences were uncovered suggesting further study is necessary before successful implementation can occur. Positive response from surveys suggests there is interest in and potential for educational implementation and use of cell phones as learning tools in schools. This study investigates college freshman students’ reflective perceptions of potential high school utilization of cell phones by students and teachers as educational learning tools. Most administrators and teachers regard cell phone possession and usage as a negative distraction and deterrent to learning rather than as an educational learning tool. High school students are prohibited from using cell phones during the school day within most public schools in the United States the majority of students, however, maintain possession of a personal cell phone within the high school setting. Student Reflective Perceptions of High School Educational Cell Phone Technology Usage
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"What on earth for? Isn't that nearly ten miles from the bakery?" Reniadis nodded, shrugging as she pulled the tarts out and set them on the table. "My father made the trek to the top of the citadel today." Chantrelle tilted her head. I wasn't expecting you today." Reniadis smiled again, hugging Maedry before moving to Chantrelle, setting down the basket only when the second woman released her. "Reniadis! It's so good to see you, dear. The elder cousin set down the quill in her hand and went to embrace the girl. The cousins looked up as the baker's daughter entered the room, both flashing bright smiles that she returned. Curly brunette hair and deep green eyes were apparently a dominant trait in the family. Lady Chantrelle was a few years Maedry's younger, closer in age to Reniadis herself, but the cousins still seemed as though they could be sisters. As a pleasant surprise, her younger cousin sat across from her, darning a sock. She stood in the middle of the kitchen, quill in hand as she looked over the parchment laid out before her. She still held the glow of youth, with a few grey strands peaking through the brunette curls, and Reniadis always felt comfortable with her around. Lady Maedry was a woman near the age of Laedliel, and rather motherly herself. It was a clean and organized space with natural light pouring in through several windows. Given that the house was still relatively small, at least in comparison to the large estates of the higher nobles, the kitchen remained on the same level as the dining room. "Thank you." She made her way through the home to the kitchens. She won't mind if you just go on in." Reniadis smiled again. ![]() "M'lady is in the kitchen, going over the menu for this week. Seconds later, it opened to reveal one of the maids, Realis, and the two women shared a smile as Reniadis was gestured inside. After the long walk, Reniadis was glad to have a moment of rest as she knocked on the door. ![]() The first stop was to be Lady Maedry, with two loaves of bread to last the next week. The two cousins lived across from each other, Lady Maedry on the left and Lady Chantrelle on the right, the latter of the two being the one with a window that overlooked the town below and out toward the woods at the foot of the mountain by which the citadel was cradled. The shop was implemented during the June 19th 2010 update of Transformice. It contains items (hats, glasses, and accessories), which you can buy with your collected cheese (one cheese is equal to one dollar) and/or fraises. Hats, glasses, and accessories can be worn at the same Cheese that is spent to buyĬlothing does not decrease the amount of cheese collected within the Time, but only one of each type can be worn simultaneously. ![]() The shop can be accessed through the Menu -> Shop.Ĭlicking the button with the cost on it will buy the item shown above it. Items cannot be sold or transferred to other mice. Items that you purchase are kept on your account, and you can changeīetween the ones you have whenever you want. ![]() The Ninja Headband is based on the designs of similar headbands from the Japanese cartoon and comic Naruto.The White Fedora may be a reference to the music video for Michael Jackson's " Smooth Criminal", in which he dons a white fedora.Transformice, many of the newer ones of which are inspired from various New items were implemented throughout the development of Item you currently want your character to wear. The Marge Simpson Hair is directly based upon the usual hairstyle of Marge Simpson from The Simpsons.(Limecat got his name due to the fact that pomelo fruit rinds look somewhat similar to limes.) The Pomelo Rind Helmet seems to be a reference to " Limecat", a scowling kitten wearing a pomelo "helmet" and one of many LOLcats.In essence, the cheese emblem would signify the wearer to belong to the "Cheese Village" of ninja. Cap is based on the cap worn by Mario from Super Mario Bros. The pompadour is a poofy hairstyle worn by nobles, but the specific style of pompadour used here is inspired directly by Elvis Presley's famous swirled pompadour.Both the Red Light Saber and Green Light Saber are taken from movies Star Wars.It's possible that the Viking Helm, Pumpkin Head, Skull Head, Miners Hat, Beanie, Bunny Ears, Crown, Beret, Bowler, Afro, Halo and Fez are references to hats found in Team Fortress 2.Asterix's Helmet is named after the headgear worn by Asterix the Gaul from the self-titled comic book series.The Super Saiyan Hair replicates the hair style of Goku's Super Saiyan form from the Dragon Ball series of comics and cartoons.Additionally, the Mouser Sunglasses are based off the enemy "Mouser" in the USA version of Super Mario Bros. The fish from Fish Earring is from Poisson, one of the games that preceded Transformice.The Skull Mask is very similar to the helmet worn by Barry the Chopper, who is also known as Number 66, from Fullmetal Alchemist.Viewtiful Joe's Helmet is the same helmet worn by Viewtiful Joe in the self-titled game series.The deadmau5 Hat is a hat inspired by the foam mascot head Canadian electro & house musician deadmau5 wears in his live performances.Yoshi's Eggshell looks exactly like part of a green Yoshi egg from the Super Mario Bros.The Blue Bomber's Helmet is the helmet worn by Mega Man in his self-titled game series.Urahara's Hat and Zangetsu are both from the Japanese anime Bleach."Urahara's Hat" also looks like the "Flud" in the MMORPG Dofus, another game which Melibellule does the art for. The Sonic Hair is based off Sonic the Hedgehog from the game series of the same name.Luffy's Straw Hat is easily recognizable as the signature headwear of Monkey D.The Ichigo Wig is another item directly inspired by Bleach - this time, by the main character, Ichigo Kurosaki.Curiously, Poisson reopened for a day in the same day that the Fishing Event started. Interestingly, there's also a title, "Sonic the Mouse", for a being the first to return the cheese 1,800 times. Cyclops Ruby Quartz Battle Visor is a item styled after the visor worn by Cyclops of the X-Men. ![]() The various Mane items are the exact "hair" styles of the six main characters from Generation IV of My Little Pony, Friendship is Magic.Link's Hat is the hat worn by Link - the protagonist in the The Legend of Zelda games. ![]() so, I hope this helps you to keep a VPN connection alive. ![]() I searched for a way to keep a VPN connection alive and this was one of the first hits on Google. This will retry launching the task if fails when starting.Ĭlick ok and now your task should be set and your computer will connect to VPN automatically on startup of Windows. I do recommend enabling the If the task fails, restart every: option. All of the configurations on the Settings tab can be set to what you want.These seem to cause conflicts with starting the task so you don’t want any of these. On the Conditions tab un-select all conditions.Set the action to start a program and in the Program/script field put the path to c:\AUTOVPN.bat the batch file you created in an earlier step. Click on the Actions tab and click the New button to set an action.Under Advanced settings chose to repeat the task on an interval that you are comfortable with.On the Triggers tab and create a trigger for the task and select to Begin the task At startup from the dropdown.Select Run with highest privileges then click on the Triggers tab. Select run whether user is logged on or not. Open Windows Task Scheduler and create a scheduled task named “AUTOVPN” and give it a description.Setup the VPN auto connect task in Windows Task Scheduler When you are done you should have a AUTOVPN.bat file.ģ. Save this batch file on your %systemdrive%. Replace “ DOMAINNAME\USERNAME” “ PASSWORD” with your own. Rasdial.exe “MY VPN” “ DOMAINNAME\USERNAME” “ PASSWORD“ This is helpful if the internet connection drops and comes back. This will attempt to reconnect the VPN connection if it detects that it has lost the connection. On the VPN connection Options tab set the Redialing options.However there is a setting in the VPN connection that you will want to set. I assume that you would not be reading this post if you did not already know how to create a basic VPN connection. I am not going to go through all the steps of creating a VPN connection in Windows. Create a scheduled task in Windows task scheduler that will kick off the batch file at Windows start up On this remote site I did not have a router with VPN tunnel capability. There is plenty of options including Static IPs and Multi-hop servers.I recently had a need to setup a server that would automatically connect to VPN on Windows startup. Finally, here you can select to which location you want the Surfshark application to connect automatically.There you can select the server to which you'd like to connect automatically. ![]()
Sx calypso, mint, lime, mango fruit, juice passion, house syrup, top w champagne Sx calypso, mint, lime, simple syrup, strawberries, top champagne Myers platinum rum, mint, lime, berrys, house grenadine, top champagne Myers platinum rum mint, lime, kiwi, top champagne Ketel one orange mint fresh orange lime juice angostura bitter house syrup top champagne Nolet gin canton gin apple juice house made grenadine Ketel one orange triple sec fresh lime juice white cranberry ![]() Nolet gin elder flower liquor muddle cucumber, lemons and splash of simple syrup Tequila alacran pineapple juice lime juice triple secĬiroc peach saint germain lichees juice apple juice ![]() Sx cha cha cha tequila jalapeno muddle passion fruit juice mango syrup rim salt Ketel one citroen vodka godiva chocolate liquor fresh orange juiceīushmills irish whisky champagne black beer Jack daniels whiskey canton ginger muddle basil, ginge and simple syrup champagne With bacon ham, roma tomatoes and arugula Veggie and sun-dried tomato pesto with artichokes, mushrooms, spinach, roma tomatoes and parmesanīLT Flat Bread Housemade Flatbread Topped With asian barbecue sauce, balsamic grilled red onion, spinach and sweet ginger rice Pepper jack cheese, lettuce and pico de gallo in a crisp and soft tortilla. accompanied by roasted garlic mashed potatoes and veggies served with sweet soy dipping sauce and our tangy steak sauce. served with garlic mashed potatoes and fresh asparagus Roasted garlic, bruschetta, olive tapenade and hummus with garlic flat bread served with spicy marinara and wasabi aioliĪ trio of chicken favorites including southwest egg rolls, shrimp and chicken potstickers and glazed chicken wings Three tender american-style kobe beef mini burgers on housemade rolls with a kosher dill pickle and mustard sauce Browse the whole menu or use our quick jump guide to go directly to the type section of the menu that you are looking for. Find latest deals, prices, kid’s meals and more. The shell, made of four hyperbolic paraboloids, is only 6cm thick and spans an area of 36x36m.Research and order delicious food from the up-to-date Tu Candela menu. In addition, questions of reception and current use are dealt with.Īn impressive example of shell construction can be seen in Dresden: In 1972, the civil engineer Ulrich Müther completed the Blasewitz rowing center on the banks of the Elbe. They address mutual influences, similarities such as differences in the design processes, construction and execution. The authors analyze the buildings and projects against the background of developments in architecture and engineering at the time. Their work - mainly in Mexico, Switzerland and the GDR - took place under very different political, economic, social and cultural conditions. With Félix Candela (1910-1997), Heinz Isler (1926-2009) and Ulrich Müther (1934-2011), this book examines three outstanding protagonists of this construction method. Technically advanced constructions of sensational expressiveness emerged worldwide. ![]() The high phase of concrete shell construction began in the middle of the 20th century. The book co-edited by Professor Matthias Beckh brings together the latest research contributions on three of the most important protagonists of shell construction. On November 9th the book "Candela Isler Müther - Positions on Shell Construction" was published by Birkhäuser Verlag. The company suggests that system administrators and users make use of BitLocker encryption instead to add extra security to the Windows machine and data. Unfortunately, this protection suffers from the same security flaws. When a domain controller is installed by using IFM media, the external syskey password had to be provided as well. The syskey.exe utility has also been known to be used by hackers as part of ransomware scams.Īctive Directory previously supported the use of an externally encrypted syskey for IFM media. The data that is protected by syskey is very limited and does not cover all files or data on the OS volume. Syskey is based on weak cryptography that can easily be broken in modern times. Unfortunately, the syskey encryption key and the use of syskey.exe are no longer considered secure. Other reasons provided by Microsoft are that syskey encryption is based on weak cryptography, that syskey does not protect all files of the operating system, and that syskey has been used in some ransomware attacks. ![]() Microsoft makes the change because the encryption key used by syskey is no longer considered secure. Click okay twice to complete the process.This saves the key to the hard disk of the local computer. Select Password Startup on the next screen.Select Update when the "Securing the Windows Account Database" window opens.Open a command prompt, type syskey, and hit the Enter-key.The use of syskey.exe needs to be disabled on these machines to upgrade them to the latest version of Windows 10 and Windows Server 2016: Windows 10 or Windows Server 2016 machines that are making use of syskey.exe for extra security won't upgrade to the Fall Creators Update. ![]() Starting with the release of the Windows 10 and Windows Server 2016 Fall Creators Update, syskey.exe will no longer be included in Windows.Īdditionally, Windows won't support installing an Active Directory domain controller anymore using Install-From-Media that was externally encrypted by syskey.exe. This password encrypts the SAM database so that it needs to be supplied for access to it. Syskey may also be used to add another password to the startup process of the Windows operating system. What Syskey.exe does basically is move the Security Accounts Management Database (SAM) encryption key to another location, usually a floppy drive or USB Flash drive. The tool was designed to improve the security of the Windows boot process by adding another layer of protection to it. Syskey.exe was introduced in Windows 2000, backported to Windows NT 4.0, and has been part of any version of Microsoft Windows released since then. ![]() ![]()
TMZ, while the genetically modified oncolytic HSV has a decreased However, certain types of cancer cellsĪre able to repair TMZ-induced DNA damage, leading to resistance to Of DNA alkylation and methylation damage in cancer cells ( 12). In addition, TMZ has been used inĬlinical trials for the treatment of advanced metastatic melanoma Of malignant glioma because it is able to easily pass through theīlood-brain barrier due to its low molecular weight and Temozolomide (TMZ) is an imidazotetrazine-derivedĪlkylating agent used as a first-line oral drug for the treatment Glioblastoma in clinical trials in Japan ( 7). HSV-1 vector derived from G207 with the deletion of the infectedĬell protein 47 (ICP47) gene and both copies of the γ34.5 gene Oncolytic HSV G47Δ is a third-generation replication-competent Genetically modified herpes simplex virus (HSV), has been approvedīy the US Food and Drug Administration for clinical application in Oncolytic viruses have been geneticallyĮngineered to improve both the safety of treatment and selectivity ![]() Potential novel therapeutic strategy for cancer treatment ( 4). Oncolytic virus-based therapy has been regarded as a The host immune response in infected cancer cells, which resultsįrom cancer antigen exposure in lysed cancer cells ( 3). In, and kill cancer cells via induction of cancer cell lysis and Oncolytic viruses can selectively infect, replicate Need to develop new effective therapeutic approaches for breast Response to radiotherapy and drug resistance to chemotherapy Surgery to eliminate distant metastasis, the lack of durable Including surgery, radiotherapy and chemotherapy, can successfullyĬure patients or prolong patient survival in the majority of cases,Įach of these therapies has limitations, such as the inability of Synergy between G47Δ and TMZ was at least partially mediated via TMZ‑induced acceleration of G47Δ replication, and such a synergy in breast cancer cells in vitro and in vivo provides novel insight into the future development of a therapeutic strategy against breast cancer.īreast cancer is the most common life-threateningĬancer in women globally, with an annual rate of new cases reachingġ26/100,000 women and a death rate of ~30% ( 1). The combined administration of G47Δ and TMZ also effectively suppressed breast cancer cell‑derived tumor growth in vivo, compared with the administration of G47Δ or TMZ alone. G47Δ and TMZ served a synergistic role resulting in decreased breast cancer cell viability, induction of cell cycle arrest, promotion of tumor cell apoptosis and enhancement of DNA damage response in vitro. The role of G47Δ and TMZ in suppressing tumorigenesis in vivo was investigated in a xenograft mouse model. Cell viability, flow cytometry, reverse transcription quantitative‑PCR and western blotting were performed to investigate the synergy between G47Δ and TMZ in regulating breast cancer cell behavior in vitro. ![]() The human breast cancer cell lines SK‑BR‑3 and MDA‑MB‑468 were treated with G47Δ and TMZ individually or in combination. The objective of the present study was to investigate the role and underlying mechanism of G47Δ and TMZ, in combination, in breast cancer cell tumorigenesis. However, the combined effect of G47Δ and TMZ on cancer cells, particularly on breast cancer cells, remains largely unknown. The oncolytic herpes simplex virus (HSV) G47Δ can selectively eliminate glioblastoma cells via viral replication and temozolomide (TMZ) has been clinically used to treat glioblastoma. ![]() She had been treated like a monster her whole life. That Juliette is a tough cookie is an understatement. A harsh existence where it’s tough to discover who we are, much tougher to adjust to, and most of all, tough to deal with ourselves. Most of us are susceptible to this phenomenon. That she is so preoccupied with her own problems that she can’t see that others have problems, too. Her life is a total mess, and all she can think about is herself. Many of the critiques I read portrayed Juliette as a helpless victim. Many people’s opinions about Juliette are negative. Even whether they are rebels, soldiers, or simply impoverished people making do in the face of danger, we should help them. To see someone make it this far amazes me. And yet, people keep choosing to live there. So lonely and messed up is this novel and its universe. I was at a loss for words for the first two days, so I couldn’t review anything. Unravel Me, the second volume in the series, was released on February 5, 2013. Fans of dystopian young adult fiction (or fiction in general) shouldn’t miss the Shatter Me trilogy, which is “a thrilling, high-stakes saga of self-discovery and forbidden love.” Unravel Me Book Summary Ransom Riggs, author of Miss Peregrine’s Home for Peculiar Children, says that fans of dystopian young adult fiction (or literature in general) should read the Shatter Me trilogy. And maybe her new friends may help her figure out why Warner and Adam are safe from her deadly skin.Īction-packed and romantic, Juliette’s world will appeal to readers who enjoyed the Red Queen series by Victoria Aveyard and the Darkest Minds trilogy by Alexandra Bracken. Juliette will finally have the power to fight back against The Reestablishment and try to fix her society before it completely falls apart. Come along with them on this exciting adventure and learn to harness the real power that lies inside. The unlikely bunch of rebels, bursting with remarkable skills and abilities, become their safe haven and source of renewed motivation. See our courageous heroine and her courageous companion, Adam, escape the hands of the villainous Warner in this exciting scene. She is shocked that her ultimate defence failed to stop the one person she needs protection from, and she doesn’t understand his mysterious resistance to her killing might. With only one touch from Juliette, Warner should have been dead. The highly anticipated sequel to the New York Times bestselling Shatter Me, written by Tahereh Mafi. Shadow Me (ePub/PDF) by Tahereh Mafi – Shatter Me #4.5 She can usually be found overcaffeinated and stuck in a book.2.2 Related Unravel Me Information Book Name: She was born in a small city somewhere in Connecticut and currently resides in Santa Monica, California, with her husband, Ransom Riggs, fellow bestselling author of Miss Peregrine s Home For Peculiar Children, and their young daughter. Tahereh Mafi is the New York Times bestselling author of the Shatter Me series which has been published in over 30 languages around the world. It will completely blow your expectations Tahereh Mafi truly knows how to deliver!". ![]() It blows your mind and makes you hungry for more of its amazing characters. "IGNITE ME really does ignite all five of your senses. A thrilling, high-stakes saga of self-discovery and forbidden love, the Shatter Me series is a must-read for fans of dystopian young adult literature - or any literature!" -Ransom Riggs, #1 New York Times bestselling author of Miss Peregrine s Home for Peculiar Children "Tahereh Mafi s bold, inventive prose crackles with raw emotion. I couldn t put it down." - Lauren Kate, #1 New York Times bestselling author of the Fallen series "Addictive, intense, and oozing with romance. I dare you to stop reading." - Kami Garcia, #1 New York Times bestselling co-author of the Beautiful Creatures series Decisions that might involve choosing between her heartand the life of those she loves. ![]() In this heart-racing sequel to the New York Times bestselling Shatter Me, Juliette has to make life-changing decisions between what she wants and what she thinks is right. Or from Warner, who wants Juliette more than she ever thought possible. She is free from The Reestablishment, free from their plan to use her as a weapon, and free to love Adam.īut Juliette will never be free from her lethal touch. She has found the headquarters of the rebel resistance - and people like her. Maas, Victoria Aveyard s The Red Queen, Netflix s Stranger Things and Leigh Bardugo s Six of Crows. X-Men meets The Handmaid s Tale in the second instalment in an epic and romantic YA fantasy trilogy perfect for fans of Sarah J. Category: Children Young Adult Fantasy Fiction Young Adult Fantasy Fiction |
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